Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndrome

Thrombocytopenia and microangiopathic hemolytic anemia (MAHA) with schistocytes on the blood smear are key findings in thrombotic microangiopathies (TMAs). Initial clinical evaluation of patients focuses on the distinction between primary and secondary TMA forms associated with underlying diseases or systemic disorders.

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None of the above: thrombotic microangiopathy beyond TTP and HUS

Acquired thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS) are appropriately at the top of a clinician's differential when a patient presents with a clinical picture consistent with an acute thrombotic microangiopathy (TMA).

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