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What is FAST4TMA?

Fast. Accurate. Simple. Testing.


Introducing the first ever free, at-home or in-hospital ADAMTS13 test for any patient in the US offered through the USTMA and Machaon Diagnostics. Rapid turnaround for both diagnostic and monitoring purposes.

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  • Mobile phlebotomist travels to patient for draw

  • Draw scheduled within 48 hours of request

  •  Same day resulting upon sample receipt

  •  Results interpretation consultation available


  • Courier to deliver sample to Machaon Diagnostics from hospital 24/7

  •  Same day resulting upon sample receipt

  •  Machaon results included interpretation that will be complemented by USTMA materials

  • Results interpretation consultation available

Why is it needed?

Thrombotic thrombocytopenic purpura (TTP) is a life-threatening condition, caused by a marked deficiency in the enzyme ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type-13). The rapid recognition of a patient with TTP [or TMA] is critical to starting effective treatment. Rapid ADAMTS13 testing is recommended and having results in <72 hours is considered “ideal” for diagnosing TTP(2). In addition, rapid testing of ADAMTS13 activity levels prevents either initiating or continuing unnecessary treatment in patients who have the clinical or laboratory findings similar to those of TTP(3) and is cost-effective when performed at a laboratory that can turn-around testing in <24 hours(4).

1. J Thromb Haemost. 2020;18:2496–2502.

2. J Thromb Haemost. 2020;18:2486–2495

3. Blood (2020) 136 (Supplement 1): 5–6

4.  Vox Sang. 2020 Jul;115(5):433-442.

Our Lab Partner

Machaon Diagnostics is an ADAMTS13 clinical reference laboratory, specializing in the diagnosis, treatment and monitoring of hemostatic and thrombotic conditions. Started as a collaboration of four laboratory scientists, Machaon Diagnostics has a defined vision to deliver highly customizable reference lab testing to both the healthcare and bioscience industries.

Thank you to those who made this program possible

If you are interested in supporting this program contact us

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